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Appetite reduction tends to be one of the earliest noticeable effects, often reported within the first one to two weeks , attributable in part to GLP-1 receptor activity in the hypothalamus and brainstem, which modulates satiety signalling

10.1001/jamapsychiatry.2014.2427 284

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How to Begin Your GLP-1 Journey Initial Consultation: Your first appointment includes a detailed discussion of your health history, current habits, previous weight-loss attempts, and long-term goals

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